Literature summary for 2.3.3.8 extracted from

Tosukhowong, P.; Borvonpadungkitti, S.; Prasongwatana, V.; Tungsanga, K.; Jutuporn, S.; Dissayabutr, T.; Reungjui, S.; Sriboonlue, P.
Urinary citrate excretion in patients with renal stone: roles of leucocyte ATP citrate lyase activity and potassium salts therapy (2002), Clin. Chim. Acta, 325, 71-78.

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Application

Application	Comment	Organism
medicine	renal stone patients have low urinary citrate excretion with high leukocyte ATP citrate (pro-3S)-lyase activity. In Northeast Thailand, low potassium status and a high carbohydrate and low fat diet may cause the increased enzyme activity. Hypokaliuria and high leukocyte ATP citrate (pro-3S)-lyase activity can be corrected by potassium-sodium citrate salt therapy	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leukocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + citrate + CoA	-	Homo sapiens	ADP + phosphate + acetyl-CoA + oxaloacetate	-	?

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Release 2023.1 (January 2023)