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Literature summary for 2.3.3.8 extracted from

  • Adams, I.P.; Dack, S.; Dickinson, F.M.; Ratledge, C.
    The distinctiveness of ATP:citrate lyase from Aspergillus nidulans (2002), Biochim. Biophys. Acta, 1597, 36-41.
    View publication on PubMed
Search for more literature for 2.3.3.8

Inhibitors

Inhibitors Comment Organism Structure
ADP 2 mM, 82% inhibition Aspergillus nidulans
D-fructose 2,6-diphosphate 18% inhibition Aspergillus nidulans
L-Leu 2 mM, 20% inhibition Aspergillus nidulans
malonyl-CoA 0.4 mM, 70% inhibition Aspergillus nidulans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
371000
-
 equilibrium sedimentation Aspergillus nidulans
550000
-
 gel filtration Aspergillus nidulans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + citrate + CoA Aspergillus nidulans the enzyme is regulated by the carbon source present in the medium ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus nidulans

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
19.6
-
-
 Aspergillus nidulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + citrate + CoA
-
 Aspergillus nidulans ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?
ATP + citrate + CoA the enzyme is regulated by the carbon source present in the medium Aspergillus nidulans ADP + phosphate + acetyl-CoA + oxaloacetate
-
 ?