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Literature summary for 2.3.3.14 extracted from
- Regulatory mechanism of Histidine-tagged homocitrate synthase from Saccharomyces cerevisiae: II. THEORY (2005), J. Biol. Chem., 280, 31633-31640.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Lys | binding to the less active enzyme conformer | Saccharomyces cerevisiae |  |
| Na+ | activity is simultaneously inhibited and activated. Activation by Na+ binding to the active enzyme conformer at an allosteric site. Inhibition by binding to the active site | Saccharomyces cerevisiae | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Na+ | activity is simultaneously inhibited and activated. Activation by Na+ binding to the active enzyme conformer at an allosteric site. Inhibition by binding to the active site | Saccharomyces cerevisiae | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
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