Application | Comment | Organism |
---|---|---|
medicine | expression of isoform HMGCS2 is down-regulated in 90% of Myc-dependent colon and rectum tumors. Protein expression is down-regulated preferentially in moderately and poorly differentiated carcinomas. In addition, it is also down-regulated in 80% of small intestine Myc-independent tumors | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform HMGCS2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Caco-2 cell | enzyme is a direct target of c-Myc, which represses hydroxymethylglutaryl-CoA synthase transcriptional activity | Homo sapiens | - |
colon | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
HMGCS2 | - |
Homo sapiens |