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Literature summary for 2.3.2.B14 extracted from

  • Gupta, R.; Lavollay, M.; Mainardi, J.L.; Arthur, M.; Bishai, W.R.; Lamichhane, G.
    The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin (2010), Nat. Med., 16, 466-469.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.B14

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis CDC 1551
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA agarose resin column chromatography, MonoQ column chromatography, and Superdex HR10/30 gel filtration Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 GlcNAc-MurNAc-L-Ala-D-iGluNH2-meso-diaminopimelic acid-NH2-D-Ala
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 Mycobacterium tuberculosis GlcNAc-MurNAc-L-Ala-D-iGluNH2-meso-diaminopimelic acid-NH2-D-Ala 3->3 crosslinked at the mesoDapNH2 position
-
 ?
2 GlcNAc-MurNAc-L-Ala-D-iGluNH2-meso-diaminopimelic acid-NH2-D-Ala
-
 Mycobacterium tuberculosis CDC 1551 GlcNAc-MurNAc-L-Ala-D-iGluNH2-meso-diaminopimelic acid-NH2-D-Ala 3->3 crosslinked at the mesoDapNH2 position
-
 ?
additional information gene MT2594 (Rv2518c) encodes an L,D–transpeptidase for synthesis of non-classical 3->3 cross-linkages Mycobacterium tuberculosis ?
-
 ?
additional information gene MT2594 (Rv2518c) encodes an L,D–transpeptidase for synthesis of non-classical 3->3 cross-linkages Mycobacterium tuberculosis CDC 1551 ?
-
 ?

Synonyms

Synonyms Comment Organism
L,D-transpeptidase
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 Mycobacterium tuberculosis
LdtMt2
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 Mycobacterium tuberculosis
MT2594
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 Mycobacterium tuberculosis