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Literature summary for 2.3.2.8 extracted from

  • Rai, R.; Wong, C.C.; Xu, T.; Leu, N.A.; Dong, D.W.; Guo, C.; McLaughlin, K.J.; Yates, J.R.; Kashina, A.
    Arginyltransferase regulates alpha cardiac actin function, myofibril formation and contractility during heart development (2008), Development, 135, 3881-3889.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.8

Cloned(Commentary)

Cloned (Comment) Organism
a targeting vector is constructed to generate Ate1-deficient mice Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
myofibril
-
 Mus musculus 30016
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginyl-tRNAArg + protein Mus musculus
-
 tRNAArg + L-arginyl-[protein]
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9Z2A5
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiac myocyte
-
 Mus musculus
-
heart
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginyl-tRNAArg + alpha cardiac actin
-
 Mus musculus tRNAArg + L-arginyl-[alpha cardiac actin]
-
 ?
L-arginyl-tRNAArg + protein
-
 Mus musculus tRNAArg + L-arginyl-[protein]
-
 ?

Synonyms

Synonyms Comment Organism
arginyltransferase
-
 Mus musculus
Ate1
-
 Mus musculus

General Information

General Information Comment Organism
physiological function posttranslational arginylation mediated by Ate1 is essential for cardiovascular development and angiogenesis and directly affects the myocardium structure in the developing heart Mus musculus