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Literature summary for 2.3.2.5 extracted from
- Glutaminyl cyclase activity is a characteristic feature of human cerebrospinal fluid (2008), Clin. Chim. Acta, 389, 152-159.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-Benzylimidazole | - |
Homo sapiens |  |
| N-omega-acetylhistamine | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebrospinal fluid | slightly lower glutaminyl cyclase activity in cerebrospinal fluid of multiple sclerosis patients compared to controls. The presence of glutaminyl cyclase in cerebrospinal fluid can stabilize peptides from degradation by aminopeptidases | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gln | - |
Homo sapiens | pyroglutamate + NH3 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutaminyl cyclase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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