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Literature summary for 2.3.2.23 extracted from
- An E2 ubiquitin-conjugating enzyme links diubiquitinated H2B to H3K27M oncohistone function (2024), Proc. Natl. Acad. Sci. USA, 121, e2416614121.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | Ubc-20 is the major enzyme responsible for generating diubiquitinated histone H2B. Loss of Ubc-20 restores wild-type patterns of H3K27me3 oncogenic histone mutation | Caenorhabditis elegans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CELE_F40G9.3 | - |
Caenorhabditis elegans |
| F40G9.3 | - |
Caenorhabditis elegans |
| Ubc-20 | - |
Caenorhabditis elegans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | Ubc-20 is the major enzyme responsible for generating diubiquitinated histone H2B. Loss of Ubc-20 restores wild-type patterns of H3K27me3 oncogenic histone mutation | Caenorhabditis elegans |
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