Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.23 extracted from

  • Du, X.; Hua, R.; He, X.; Hou, W.; Li, S.; Yang, A.; Yang, G.
    Echinococcus granulosus ubiquitin-conjugating enzymes (E2D2 and E2N) promote the formation of liver fibrosis in TGFbeta1-induced LX-2 cells (2024), Parasit. Vectors, 17, 190.
    View publication on PubMed
Search for more literature for 2.3.2.23

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular both isoforms E2D2 and E2N are secreted to the hydatid fluid and cystic echinococcosis-infected sheep liver tissues via a non-classical secretory pathway Echinococcus granulosus
-
-

Organism

Organism UniProt Comment Textmining
Echinococcus granulosus A0A5C1ZXC4
-
-
Echinococcus granulosus U6JN29
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cyst wide distribution in the germinal layer of the fertile cysts Echinococcus granulosus
-
protoscolex
-
 Echinococcus granulosus
-

Subunits

Subunits Comment Organism
? x * 16000, calculated from sequence Echinococcus granulosus

Synonyms

Synonyms Comment Organism
E2D2
-
 Echinococcus granulosus
E2N
-
 Echinococcus granulosus

pI Value

Organism Comment pI Value Maximum pI Value
Echinococcus granulosus calculated from sequence
-
 6.4

General Information

General Information Comment Organism
physiological function both isoforms E2D2 and E2N promote the expression of fibrogenic genes when added to TGFbeta1-induced LX-2 cells and promote the proliferation and migration of TGFbeta1-induced LX-2 cells Echinococcus granulosus