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Literature summary for 2.3.2.23 extracted from
- Identification of ubiquitin variants that inhibit the E2 ubiquitin conjugating enzyme, Ube2k (2021), ACS Chem. Biol., 16, 1745-1756.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | identification of ubiquitin variants that bind tightly and specifically to Ube2k at a hydrophobic cleft that is distinct from the active site and ubiquitin binding sites. The variants are potent inhibitors of Ube2k and block both ubiquitin charging of the E2 enzyme and E3-catalyzed ubiquitin transfer | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P61086 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UBE2K | - |
Homo sapiens |
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