Literature summary for 2.3.2.2 extracted from

Sener, A.; Yardimci, T.
Activity determination, kinetic analyses and isoenzyme identification of gamma glutamyltransferase in human neutrophils (2005), J. Biochem. Mol. Biol., 38, 343-349.

Search for more literature for 2.3.2.2

Inhibitors

Inhibitors	Comment	Organism	Structure
Bromocresol green	0.01 mM, 31% inhibition, noncompetitive	Homo sapiens
L-Ser	in presence of borate, competitive	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.8	-	5-L-glutamyl-4-nitroanilide	-	Homo sapiens
16.9	-	glycylglycine	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
neutrophil	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-L-glutamyl-4-nitroanilide + glycylglycine	-	Homo sapiens	4-nitroaniline + 5-L-glutamylglycylglycine	-	?

Synonyms

Synonyms	Comment	Organism
GGT	-	Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	-	Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
56	-	30 min, 42% loss of activity	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8.2	-	-	Homo sapiens

pH Range

pH Minimum	pH Maximum	Comment	Organism
6.5	9	pH 6.5: about 50% of maximal activity, pH 9.0: about 90% of maximal activity	Homo sapiens

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Release 2023.1 (January 2023)