Any feedback?
Literature summary for 2.3.2.13 extracted from
- Activation and inhibition of transglutaminase 2 in mice (2012), PLoS ONE, 7, e30642.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| polyinosinic-polycytidylic acid | treatment with 15-30 mg/kg polyinosinic-polycytidylic acid results in villous atrophy and activation of TG2 at the villus tips in small intestine | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ERW1041E | - |
Mus musculus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| duodenum | - |
Mus musculus | - |
| ileum | - |
Mus musculus | - |
| jejunum | - |
Mus musculus | - |
| small intestine | enzyme activity is most pronounced in the duodenum, and decreased progressively in the jejunum and ileum | Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TG2 | - |
Mus musculus |
| tissue transglutaminase | - |
Mus musculus |
| transglutaminase 2 | - |
Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
