Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pacifastacus leniusculus | Q964D3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
granule cell | mRNA expression and TGase enzyme activity are high in hematopoietic cells, less in the semi-granular hemocyte and very low in the granular cells | Pacifastacus leniusculus | - |
hematopoietic system | TGase is one of the most abundant proteins in hematopoietic tissue. mRNA expression and enzyme activity are high in hematopoietic cells, less in the semi-granular hemocyte and very low in the granular cells | Pacifastacus leniusculus | - |
hemocyte | mRNA expression and TGase enzyme activity are high in hematopoietic cells, less in the semi-granular hemocyte and very low in the granular cells | Pacifastacus leniusculus | - |
General Information | Comment | Organism |
---|---|---|
physiological function | complete knock-down by RNAi results in changed cell morphology, and cells start to spread intensely. After addition of astakine, a cytokine involved in hematopoiesis, cells start to spread and adopt a morphology similar to that observed after RNAi of TGase. Astakine has no effect on TGase expression, but after a prolonged incubation for one week, TGase activity inside and outside the cells is completely lost | Pacifastacus leniusculus |