Literature summary for 2.3.2.13 extracted from

Lin, X.; Soederhaell, K.; Soederhaell, I.
Transglutaminase activity in the hematopoietic tissue of a crustacean, Pacifastacus leniusculus, importance in hemocyte homeostasis (2008), BMC Immunol., 9, 58.

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Organism

Organism	UniProt	Comment	Textmining
Pacifastacus leniusculus	Q964D3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
granule cell	mRNA expression and TGase enzyme activity are high in hematopoietic cells, less in the semi-granular hemocyte and very low in the granular cells	Pacifastacus leniusculus	-
hematopoietic system	TGase is one of the most abundant proteins in hematopoietic tissue. mRNA expression and enzyme activity are high in hematopoietic cells, less in the semi-granular hemocyte and very low in the granular cells	Pacifastacus leniusculus	-
hemocyte	mRNA expression and TGase enzyme activity are high in hematopoietic cells, less in the semi-granular hemocyte and very low in the granular cells	Pacifastacus leniusculus	-

General Information

General Information	Comment	Organism
physiological function	complete knock-down by RNAi results in changed cell morphology, and cells start to spread intensely. After addition of astakine, a cytokine involved in hematopoiesis, cells start to spread and adopt a morphology similar to that observed after RNAi of TGase. Astakine has no effect on TGase expression, but after a prolonged incubation for one week, TGase activity inside and outside the cells is completely lost	Pacifastacus leniusculus

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Release 2023.1 (January 2023)