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Literature summary for 2.3.2.13 extracted from

  • Chica, R.A.; Gagnon, P.; Keillor, J.W.; Pelletier, J.N.
    Tissue transglutaminase acylation: proposed role of conserved active site Tyr and Trp residues revealed by molecular modeling of peptide substrate binding (2004), Protein Sci., 13, 979-991.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.13

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.9
-
 CBz-Gln-Ala 37°C, pH 7.0 Pagrus major
2.7
-
 CBZ-Gln-Phe 37°C, pH 7.0 Pagrus major
2.9
-
 CBz-Gln-Ser 37°C, pH 7.0 Pagrus major
3.2
-
 CBz-Gln-Gly 37°C, pH 7.0 Pagrus major
4.4
-
 CBz-Gln-Val 37°C, pH 7.0 Pagrus major
7
-
 CBz-Gln-Leu 37°C, pH 7.0 Pagrus major
9.4
-
 CBz-Gln-Gly-Gly 37°C, pH 7.0 Pagrus major

Organism

Organism UniProt Comment Textmining
Pagrus major
-
 red sea bream
-

Reaction

Reaction Comment Organism Reaction ID
protein glutamine + alkylamine = protein N5-alkylglutamine + NH3 model for binding and reaction of small peptide substrates, via Michaelis-complex Pagrus major
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no substrate: Boc-Gln-Gly Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + CBz-Gln-Ala
-
 Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + Cbz-Gln-Gly
-
 Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + CBz-Gln-Gly-Gly
-
 Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + CBz-Gln-Leu
-
 Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + CBZ-Gln-Phe
-
 Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + CBz-Gln-Ser
-
 Pagrus major ?
-
 ?
N,N-dimethyl-1,4-phenylenediamine + CBz-Gln-Val
-
 Pagrus major ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
51
-
 CBz-Gln-Ala 37°C, pH 7.0 Pagrus major
54
-
 CBZ-Gln-Phe 37°C, pH 7.0 Pagrus major
66
-
 CBz-Gln-Ser 37°C, pH 7.0 Pagrus major
71
-
 CBz-Gln-Val 37°C, pH 7.0 Pagrus major
96
-
 CBz-Gln-Gly 37°C, pH 7.0 Pagrus major
102
-
 CBz-Gln-Gly-Gly 37°C, pH 7.0 Pagrus major
127
-
 CBz-Gln-Leu 37°C, pH 7.0 Pagrus major