Cloned (Comment) | Organism |
---|---|
expression of transglutaminase 1 in Sf9 insect cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GTP | 0.02-0.1 mM, inhibition of transglutaminases 2 and 3 | Homo sapiens | |
additional information | transglutaminase 1, not inhibited by GTP | Homo sapiens | |
S-nitroso-N-acetylpenicillamine | NO-donor, 8-16 mM, almost complete inhibition of transglutaminases 1 and 3, weak inhibition of transglutaminase 3 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | transglutaminase 1, membrane-anchored | Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
recombinant transglutaminase 1, gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant transglutaminase 1, DEAE-Sephacel, heparin-Sepharose, gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin | transglutaminase 1, required for the formation of a cornified envelope in stratified squamous epithelia | Homo sapiens | - |