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Literature summary for 2.3.2.13 extracted from
- Purification and molecular characterization of a secretory transglutaminase from coagulating gland of the rat (1991), Biochim. Biophys. Acta, 1078, 139-146.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | complete inactivation above 10 mM | Rattus norvegicus |  |
| additional information | transglutaminase of coagulating gland, not inhibited by GTP | Rattus norvegicus | |
| NH4+ | complete inhibition of coagulating gland transglutaminase with more than 1 mM NH4Cl or 20 mM (NH4)2SO4 | Rattus norvegicus | |
| Sodium citrate | above 10 mM, complete inactivation | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | requirement | Rattus norvegicus | |
| Ca2+ | 0.5 mM, maximum activity of transglutaminase from coagulating gland | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
transglutaminase C, gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
mature male Wistar | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | coagulating gland transglutaminase, glycosylated with mannosyl-residues, no terminal position, substituted with saturated acyl residues and phosphoinositol | Rattus norvegicus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| coagulating gland | secretion, not immunologically related to tissue-type enzyme or blood factor XIIIa | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| putrescine + N,N'-dimethylcasein | - |
Rattus norvegicus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| additional information | - |
pI: 8.5-8.7, purified enzyme | Rattus norvegicus |
| additional information | - |
pI: 7.6, crude enzyme | Rattus norvegicus |
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