Literature summary for 2.3.2.12 extracted from

Ramu, H.; Vazquez-Laslop, N.; Klepacki, D.; Dai, Q.; Piccirilli, J.; Micura, R.; Mankin, A.S.
Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center (2011), Mol. Cell, 41, 321-330.

Search for more literature for 2.3.2.12

Inhibitors

Inhibitors	Comment	Organism	Structure
arginine attenuator peptide	the wild type arginine attenuator peptide (AAP) inhibits peptidyl transferase center (PTC) function. AAP containing the D12N mutation, which eliminates Arg-induced ribosome stalling, also eliminates Arg's effect on PTC function	Neurospora crassa
L-arginine	-	Neurospora crassa
additional information	the peptidyl transferase center is not inhibited by D-arginine	Neurospora crassa

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
ribosome	-	Neurospora crassa	5840	-

Organism

Organism	UniProt	Comment	Textmining
Neurospora crassa	-	-	-

Synonyms

Synonyms	Comment	Organism
PTC	peptidyl transferase center	Neurospora crassa

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Release 2023.1 (January 2023)