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Literature summary for 2.3.2.12 extracted from
- New aspects on the kinetics of activation of ribosomal peptidyltransferase-catalyzed peptide bond formation by monovalent ions and spermine (1997), Biochim. Biophys. Acta, 1342, 182-190.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| K+ | stimulation not so marked as that caused by NH4+ ions | Escherichia coli |  |
| NH4+ | combination of NH4+ ions with spermine produces an additive activity increase | Escherichia coli | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| spermine | in the absence of factors washable from ribosomes | Escherichia coli | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| ribosome | additionally factors washable from ribosomes | Escherichia coli | 5840 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
B cells, frozen | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| AcPhe-tRNA + puromycin | AcPhe-tRNA-polyU-ribosome complex | Escherichia coli | tRNA + AcPhe-puromycin | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
enzyme assay | Escherichia coli |
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