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BRENDA support

Literature summary for 2.3.1.B43 extracted from

  • Roessler, C.; Tueting, C.; Meleshin, M.; Steegborn, C.; Schutkowski, M.
    A novel continuous assay for the deacylase sirtuin 5 and other deacetylases (2015), J. Med. Chem., 58, 7217-7223.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NXA8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + [carbamoyl phosphate synthetase 1 derived glutarylated peptide]-N6-acetyl-L-lysine
-
Homo sapiens nicotinamide + [carbamoyl phosphate synthetase 1 derived glutarylated peptide]-L-lysine + 2'-O-acetyl-ADP-ribose
-
?

Synonyms

Synonyms Comment Organism
SIRT5
-
Homo sapiens
sirtuin 5
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+ dependent on Homo sapiens