Crystallization (Comment) | Organism |
---|---|
vapor diffusion at 20°C, crystal structure of the enzyme bound to KGLGKGGA(N6-succinyl)KRHRKW | Archaeoglobus fulgidus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Archaeoglobus fulgidus | O28597 | - |
- |
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
- |
Archaeoglobus fulgidus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + KGLGKGGA(N6-acetyl)KRHRKW | the rate of desuccinylation is 2.3fold faster than the rate of deacetylation | Escherichia coli | nicotinamide + KGLGKGGAKRHRKW + 2'-O-acetyl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-acetyl)KRHRKW | the rate of desuccinylation is about 5fold faster than the rate of deacetylation | Archaeoglobus fulgidus | nicotinamide + KGLGKGGAKRHRKW + 2'-O-acetyl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-butyryl)KRHRKW | the rate of desuccinylation is 5.8fold faster than the rate of deburyrylation | Escherichia coli | nicotinamide + KGLGKGGAKRHRKW + 2'-O-butyryl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-butyryl)KRHRKW | the rate of desuccinylation is about 10fold faster than the rate of debutyrylation | Archaeoglobus fulgidus | nicotinamide + KGLGKGGAKRHRKW + 2'-O-butyryl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-propionyl)KRHRKW | the rate of desuccinylation is 3.8fold faster than the rate of depropionylation | Escherichia coli | nicotinamide + KGLGKGGAKRHRKW + 2'-O-propionyl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-propionyl)KRHRKW | the rate of desuccinylation is about 5fold faster than the rate of depropionylation | Archaeoglobus fulgidus | nicotinamide + KGLGKGGAKRHRKW + 2'-O-propionyl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-succinyl)KRHRKW | the rate of desuccinylation is 2.3fold faster than the rate of deacetylation | Escherichia coli | nicotinamide + KGLGKGGAKRHRKW + 2'-O-succinyl-ADP-ribose | - |
? | |
NAD+ + KGLGKGGA(N6-succinyl)KRHRKW | the rate of desuccinylation is about 5fold faster than the rate of deacetylation | Archaeoglobus fulgidus | nicotinamide + KGLGKGGAKRHRKW + 2'-O-succinyl-ADP-ribose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CobB | - |
Escherichia coli |
Sir2Af1 | - |
Archaeoglobus fulgidus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Escherichia coli |
50 | - |
assay at | Archaeoglobus fulgidus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Escherichia coli |
8 | - |
assay at | Archaeoglobus fulgidus |