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Literature summary for 2.3.1.97 extracted from

  • Charavaryamath, C.; Lemieux, H.; Singh Suri, S.; Selvakumar, P.; Sharma, R.K.; Singh, B.
    Expression and activities of N-myristoyltransferase and calcineurin in normal and inflamed lungs (2009), Exp. Lung Res., 35, 729-747.
    View publication on PubMed
Search for more literature for 2.3.1.97

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus the enzyme catalyzes the cotranslational irreversible addition of a fatty acyl moiety to the N-terminus of proteins ?
-
 ?
tetradecanoyl-CoA + glycylpeptide Rattus norvegicus
-
 CoA + N-tetradecanoyl-glycylpeptide
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
blood vessel wall Rattus norvegicus
-
epithelium airway Rattus norvegicus
-
lung septa and alveolar macrophages Rattus norvegicus
-
macrophage alveolar Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme catalyzes the cotranslational irreversible addition of a fatty acyl moiety to the N-terminus of proteins Rattus norvegicus ?
-
 ?
tetradecanoyl-CoA + glycylpeptide
-
 Rattus norvegicus CoA + N-tetradecanoyl-glycylpeptide
-
 ?

Synonyms

Synonyms Comment Organism
N-myristoyltransferase
-
 Rattus norvegicus
NMT
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
 assay at Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus lipopolysaccharides increase the enzyme expression in lungs up