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Literature summary for 2.3.1.97 extracted from

  • King, M.J.; Sharma, R.K.
    Differential activation of bovine brain N-myristoyltransferase(s) by a cytosolic activator (1995), Biochem. Biophys. Res. Commun., 212, 580-588.
    View publication on PubMed
Search for more literature for 2.3.1.97

Activating Compound

Activating Compound Comment Organism Structure
N-myristoyltransferase activator NAF45 increase of Km for peptide substrates Bos taurus
N-myristoyltransferase activator NAF45 absolutely required for activity of brain enzyme isoforms, maximal 3-4fold activation Bos taurus
N-myristoyltransferase activator NAF45 from brain, 45 kDa protein Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
factor NIP71 competitive against activation factor NAF45 Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 at least 4 isoforms in the brain
-

Purification (Commentary)

Purification (Comment) Organism
isoform from brain bound to NAF45 Bos taurus

Renatured (Commentary)

Renatured (Comment) Organism
reconstitution of activity by rebuilding enzyme-NAF45 complex Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myristoyl-CoA + cAMP-dependent protein kinase-derived peptide
-
 Bos taurus N-myristoylated cAMP-dependent protein kinase-derived peptide + CoA
-
 ?
myristoyl-CoA + glycylpeptide specific for Gly at N-terminus Bos taurus N-myristoylglycylpeptide + CoA
-
 ?
myristoyl-CoA + p60src-derived peptide
-
 Bos taurus N-myristoylated p60src-derived peptide + CoA
-
 ?

Synonyms

Synonyms Comment Organism
NMT
-
 Bos taurus