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Literature summary for 2.3.1.97 extracted from

  • Boutin, J.A.; Clarenc, J.P.; Ferry, G.; Ernould, A.P.; Remond, G.; Vincent, M.; Atassi, G.
    N-myristoyl-transferase activity in cancer cells. Solubilization, specificity and enzymatic inhibition of a N-myristoyl transferase from L1210 microsomes (1991), Eur. J. Biochem., 201, 257-263.
    View publication on PubMed
Search for more literature for 2.3.1.97

Activating Compound

Activating Compound Comment Organism Structure
deoxycholate 2% w/v, activation by pretreatment Mus musculus
deoxycholate 2% w/v, activation by pretreatment Rattus norvegicus
Triton 770 2% w/v, activation by pretreatment Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Mus musculus
additional information
-
 additional information
-
 Rattus norvegicus
additional information
-
 additional information
-
 Saccharomyces cerevisiae
0.033
-
 Gly-Ser-Ser-Lys-Pro-Lys-Asp-Lys-Asp-Pro
-
 Mus musculus
0.17
-
 Gly-Gln-Thr-Val-Thr-Thr-Pro-Leu
-
 Mus musculus
0.33
-
 Gly-Asn-Ala-Ala-Ala-Arg-Arg
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Mus musculus
-
-
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
brain
-
 Rattus norvegicus
-
L-1210 cell leukemic cell line Mus musculus
-
liver
-
 Mus musculus
-
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0000019
-
 microsomes from brain Rattus norvegicus
0.0000021
-
 microsomes from leukemia cell line L1210 Mus musculus
0.0000076
-
 microsomes from liver Mus musculus
0.000146
-
 microsomes Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg
-
 Mus musculus N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg + CoA
-
 ?
myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg
-
 Rattus norvegicus N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg + CoA
-
 ?
myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg
-
 Saccharomyces cerevisiae N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg + CoA
-
 ?
myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Arg-Arg
-
 Mus musculus N-myristoyl-Gly-Asn-Ala-Ala-Ala-Arg-Arg + CoA
-
 ?
myristoyl-CoA + Gly-Gln-Thr-Val-Thr-Thr-Pro-Leu
-
 Mus musculus N-myristoyl-Gly-Gln-Thr-Val-Thr-Thr-Pro-Leu + CoA
-
 ?
myristoyl-CoA + Gly-Ser-Ser-Lys-Pro-Lys-Asp-Lys-Asp-Pro
-
 Mus musculus N-myristoyl-Gly-Ser-Ser-Lys-Pro-Lys-Asp-Lys-Asp-Pro + CoA
-
 ?
myristoyl-CoA + glycylpeptide
-
 Mus musculus N-myristoylglycylpeptide + CoA
-
 ?
myristoyl-CoA + glycylpeptide
-
 Rattus norvegicus N-myristoylglycylpeptide + CoA
-
 ?
myristoyl-CoA + glycylpeptide
-
 Saccharomyces cerevisiae N-myristoylglycylpeptide + CoA
-
 ?

Synonyms

Synonyms Comment Organism
NMT
-
 Mus musculus
NMT
-
 Rattus norvegicus
NMT
-
 Saccharomyces cerevisiae