Any feedback?
Literature summary for 2.3.1.97 extracted from
- The biology and enzymology of eukaryotic protein acylation (1988), Annu. Rev. Biochem., 57, 69-99.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | - |
Mus musculus | |
| additional information | - |
Rattus norvegicus | |
| additional information | overview: inhibition by glycylpeptides with varying amino acids at positions 2 to 8 | Saccharomyces cerevisiae |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Mus musculus | |
| additional information | - |
additional information | - |
Rattus norvegicus | |
| additional information | - |
additional information | overview: Km values for glycylpeptides with varying amino acids sequence, influence of amino acid residue type and substitutions on affinity | Saccharomyces cerevisiae | |
| additional information | - |
additional information | overview: Km values for glycylpeptides with varying amino acids sequence, influence of amino acid residue type and substitutions on affinity | Triticum aestivum | |
| 0.0004 | - |
myristoyl-CoA | - |
Saccharomyces cerevisiae |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Mus musculus | 16020 | - |
| membrane | - |
Rattus norvegicus | 16020 | - |
| membrane | peripheral membrane protein | Saccharomyces cerevisiae | 16020 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55000 | - |
- |
Rattus norvegicus |
| 55000 | - |
- |
Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
| Triticum aestivum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| tetradecanoyl-CoA + an N-terminal-glycyl-[protein] = CoA + an N-terminal-N-tetradecanoylglycyl-[protein] | mechanism | Saccharomyces cerevisiae |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| germ | - |
Triticum aestivum | - |
| liver | - |
Mus musculus | - |
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myristoyl-CoA + glycylpeptide | substrate specificity | Mus musculus | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | substrate specificity | Rattus norvegicus | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | substrate specificity | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | substrate specificity | Triticum aestivum | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | specific for uncharged amino acid at position 2 of peptide chain, no peptides with bulky hydrophobic side chains at position 2, broad spectrum of amino acids in position 3, overview | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | specific for Gly at N-terminus | Rattus norvegicus | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | specific for Gly at N-terminus | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | specific for myristoyl-CoA | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | p60src-derived peptides | Rattus norvegicus | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | p60src-derived peptides | Saccharomyces cerevisiae | N-myristoylglycylpeptide + CoA | - |
? | |
| palmitoyl-CoA + glycylpeptide | poor substrate | Saccharomyces cerevisiae | N-palmitoylglycylpeptide + CoA | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 55000, SDS-PAGE | Rattus norvegicus |
| monomer | 1 * 55000, SDS-PAGE | Saccharomyces cerevisiae |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NMT | - |
Mus musculus |
| NMT | - |
Rattus norvegicus |
| NMT | - |
Saccharomyces cerevisiae |
| NMT | - |
Triticum aestivum |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | overview: Ki values for glycylpeptides with varying amino acids at positions 2 to 5 | Saccharomyces cerevisiae |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
