Literature summary for 2.3.1.95 extracted from

Schwekendiek, A.; Spring, O.; Heyerick, A.; Pickel, B.; Pitsch, N.T.; Peschke, F.; de Keukeleire, D.; Weber, G.
Constitutive expression of a grapevine stilbene synthase gene in transgenic hop (Humulus lupulus L.) yields resveratrol and its derivatives in substantial quantities (2007), J. Agric. Food Chem., 55, 7002-7009.

Cloned(Commentary)

Cloned (Comment)	Organism
Humulus lupulus plants of the Tettnang variety are transformed with a gene encoding for STS from grapevine. Under the control of the constitutive 35S cauliflower mosaic virus promoter, expression of the transgene results in accumulation of resveratrol and high levels of its glycosylated derivatives in leaves and inflorescences. Piceid, the predominant derivative, reaches a concentration of up to 560 microg/g of fresh weight in hop cones, whereas no stilbenes are detected in nontransformed controls (wild type). In Humulus lupulus constitutive expression of sts interferes neither with plant development nor with the biosynthesis of secondary metabolites relevant for the brewing industry. Since resveratrol is a well-known phytoalexin and antioxidant, transgenic Humulus lupulus plants could display enhanced pathogen resistance against microbial pathogens, exhibit new beneficial properties for health, and open new venues for metabolic engineering	Vitis vinifera

Cloned (Comment)

Organism

Humulus lupulus plants of the Tettnang variety are transformed with a gene encoding for STS from grapevine. Under the control of the constitutive 35S cauliflower mosaic virus promoter, expression of the transgene results in accumulation of resveratrol and high levels of its glycosylated derivatives in leaves and inflorescences. Piceid, the predominant derivative, reaches a concentration of up to 560 microg/g of fresh weight in hop cones, whereas no stilbenes are detected in nontransformed controls (wild type). In Humulus lupulus constitutive expression of sts interferes neither with plant development nor with the biosynthesis of secondary metabolites relevant for the brewing industry. Since resveratrol is a well-known phytoalexin and antioxidant, transgenic Humulus lupulus plants could display enhanced pathogen resistance against microbial pathogens, exhibit new beneficial properties for health, and open new venues for metabolic engineering

Vitis vinifera

Organism

Organism	UniProt	Comment	Textmining
Vitis vinifera	-	-	-

Synonyms

Synonyms	Comment	Organism
STS	-	Vitis vinifera

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Release 2023.1 (January 2023)