Cloned (Comment) | Organism |
---|---|
heterologous expression in Streptomyces coelicolor and Escherichia coli | Saccharopolyspora erythraea |
Crystallization (Comment) | Organism |
---|---|
- |
Saccharopolyspora erythraea |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH + 6 H+ | Saccharopolyspora erythraea | - |
6-deoxyerythronolide B + 7 CoA + 6 CO2 + H2O + 6 NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharopolyspora erythraea | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Saccharopolyspora erythraea |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH + 6 H+ | - |
Saccharopolyspora erythraea | 6-deoxyerythronolide B + 7 CoA + 6 CO2 + H2O + 6 NADP+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
oligomer | the polyketide product is synthesized by the processive action of a loading didomain, six extension modules and a terminal thioesterase domain, as a minimal requirement for chain extension, each module contains a set of three functional domains, a ketosynthase, an acyltransferae, and an acyl carrier protein | Saccharopolyspora erythraea |
Synonyms | Comment | Organism |
---|---|---|
6-deoxyerythronolide B synthase | - |
Saccharopolyspora erythraea |
DEBS | - |
Saccharopolyspora erythraea |
PKS | - |
Saccharopolyspora erythraea |
polyketide synthase | - |
Saccharopolyspora erythraea |