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Literature summary for 2.3.1.86 extracted from

  • Gajewski, J.; Pavlovic, R.; Fischer, M.; Boles, E.; Grininger, M.
    Engineering fungal de novo fatty acid synthesis for short chain fatty acid production (2017), Nat. Commun., 8, 14650.
    View publication on PubMed
Search for more literature for 2.3.1.86

Protein Variants

Protein Variants Comment Organism
I306A/G1250S mutant displays best production of hexanoic acid, accounting for 90% of measured short-chain fatty acids, yield is 20 mg/l Saccharomyces cerevisiae
I306A/G1250S/M1250W mutant displays increased synthesis of short-chain fatty acids, yield is up to 66 mg/l Saccharomyces cerevisiae
I306A/R1834K/F1279Y mutant displays best production of octanoic acid, yield is 48 mg/l Saccharomyces cerevisiae
I306A/R1834K/G1250S mutant displays increased synthesis of short-chain fatty acids, yield is up to 118 mg/l Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P07149 and P19097 P07149 i.e. subunit FAS1, P19097 i.e. subunit FAS2
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