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Literature summary for 2.3.1.86 extracted from

  • Nguyen, L.N.; Trofa, D.; Nosanchuk, J.D.
    Fatty acid synthase impacts the pathobiology of Candida parapsilosis in vitro and during mammalian infection (2009), PLoS ONE, 4, e8421.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.86

Application

Application Comment Organism
medicine potential treatment of infection of humans with Candida parapsilosis Candida parapsilosis

Protein Variants

Protein Variants Comment Organism
additional information FAS2 KO cells, construction of Fas2 disruptants influences virulence, unability to form normal biofilms Candida parapsilosis

Inhibitors

Inhibitors Comment Organism Structure
cerulenin
-
 Candida parapsilosis

Organism

Organism UniProt Comment Textmining
Candida parapsilosis
-
-
-

Synonyms

Synonyms Comment Organism
CpFas2
-
 Candida parapsilosis
fas2
-
 Candida parapsilosis
fatty acid synthase
-
 Candida parapsilosis

General Information

General Information Comment Organism
malfunction construction of Fas2 disruptants influences virulence, unability to form normal biofilms Candida parapsilosis
physiological function essential for growth in absence of exogenous fatty acids, involved in unsatured fatty acid production Candida parapsilosis