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Literature summary for 2.3.1.86 extracted from
- Fatty acid synthase impacts the pathobiology of Candida parapsilosis in vitro and during mammalian infection (2009), PLoS ONE, 4, e8421.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | potential treatment of infection of humans with Candida parapsilosis | Candida parapsilosis |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | FAS2 KO cells, construction of Fas2 disruptants influences virulence, unability to form normal biofilms | Candida parapsilosis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cerulenin | - |
Candida parapsilosis |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida parapsilosis | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CpFas2 | - |
Candida parapsilosis |
| fas2 | - |
Candida parapsilosis |
| fatty acid synthase | - |
Candida parapsilosis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | construction of Fas2 disruptants influences virulence, unability to form normal biofilms | Candida parapsilosis |
| physiological function | essential for growth in absence of exogenous fatty acids, involved in unsatured fatty acid production | Candida parapsilosis |
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