Application | Comment | Organism |
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medicine | two isolates resistant to fluoroquinolones and beta-lactam antimicrobials show mutations in the quinolone resistance-determining regions of gene GyrA and of ParC as well as carrying a 150 kb plasmid harbouring the quinolone resistance gene qnrA1, the ciprofloxacin-modifying enzyme-encoding gene aac(6')-Ib-cr and genes encoding for extended-spectrum beta-lactamases such as blaSHV and blaCTX-M-3. When this large plasmid is transferred to Escherichia coli by conjugation, the transconjugants show a 10-75fold increase in the minimum inhibitory concentrations of ciprofloxacin and norfloxacin | Vibrio fluvialis |
Organism | UniProt | Comment | Textmining |
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Vibrio fluvialis | - |
- |
- |