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Literature summary for 2.3.1.76 extracted from
- Esterification and hydrolysis of vitamin A in the liver of brook trout (Salvelinus fontinalis) and the influence of a coplanar polychlorinated biphenyl (1999), Comp. Biochem. Physiol. C, 122C, 317-325.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | retinyl esterification: storage of vitamin A | Salvelinus fontinalis |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not inhibited by 3,3',4,4'-tetrachlorobiphenyl | Salvelinus fontinalis |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.016 | - |
retinol | - |
Salvelinus fontinalis |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | membrane fraction | Salvelinus fontinalis | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + retinol | Salvelinus fontinalis | - |
CoA + retinyl ester | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Salvelinus fontinalis | - |
fish, brook trout | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial purification by differential centrifugation | Salvelinus fontinalis |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Salvelinus fontinalis | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
activity determined from microsomes | Salvelinus fontinalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acyl-CoA + retinol | - |
Salvelinus fontinalis | CoA + retinyl ester | - |
? | |
| palmitoyl-CoA + retinol | - |
Salvelinus fontinalis | CoA + retinylpalmitate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 12 | - |
assay at | Salvelinus fontinalis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
maximal activity | Salvelinus fontinalis |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 3 | 11 | decreasing activity below pH 5 | Salvelinus fontinalis |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 11 | activity is decreased below | Salvelinus fontinalis |
| 7.8 | - |
Tris-HCl buffer | Salvelinus fontinalis |
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