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Literature summary for 2.3.1.74 extracted from
- In vitro inhibition of carrot chalcone synthase by 3'-nucleotidase: the role of the 3-phosphate group of malonyl-coenzyme A in flavonoid biosynthesis (1986), Arch. Biochem. Biophys., 246, 217-224.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3'-Nucleotidase | i.e. EC 3.1.3.6 hydrolyzes the phosphate group in the 3'-position of adenosine, a part of the CoA thioester substrates | Daucus carota | |
| malonyl-3'-dephospho-CoA | 50% inhibition at 0.003 mM | Daucus carota |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-coumaroyl-CoA + 3 malonyl-CoA | Daucus carota | - |
naringenin chalcone + 4 CoA + 3 CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Daucus carota | - |
carrot, ssp. sativa | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell suspension culture | - |
Daucus carota | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-coumaroyl-CoA + 3 malonyl-CoA | - |
Daucus carota | naringenin chalcone + 4 CoA + 3 CO2 | - |
? | |
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