Literature summary for 2.3.1.74 extracted from

Suh, D.Y.; Kagami, J.; Fukuma, K.; Sankawa, U.
Evidence for catalytic cysteine-histidine dyad in chalcone synthase (2000), Biochem. Biophys. Res. Commun., 275, 725-730.

Search for more literature for 2.3.1.74

Cloned(Commentary)

Cloned (Comment)	Organism
wild type and mutants	Pueraria montana var. lobata

Protein Variants

Protein Variants	Comment	Organism
C164S	inhibition by diethyl diphosphate is pH dependent	Pueraria montana var. lobata

Inhibitors

Inhibitors	Comment	Organism	Structure
diethyl diphosphate	inhibition of wild-type enzyme is pH independent, inhibition of C164S mutant increases with increasing pH between pH 6.2 to pH 7.4	Pueraria montana var. lobata
iodoacetamide	due to labeling of C164	Pueraria montana var. lobata

Organism

Organism	UniProt	Comment	Textmining
Pueraria montana var. lobata	-	-	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	-	Pueraria montana var. lobata

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
malonyl CoA + 4-coumaroyl-CoA + NADH	-	Pueraria montana var. lobata	6'-deoxychalcone + CoA + CO2 + NAD+	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)