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Literature summary for 2.3.1.74 extracted from

  • Ayabe, S.; Udagawa, A.; Furuya, T.
    NAD(P)H-dependent 6-deoxychalcone synthase activity in Glycyrrhiza echinata cells induced by yeast extract (1988), Arch. Biochem. Biophys., 261, 458-462.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4-coumaroyl-CoA + 3 malonyl-CoA Glycyrrhiza echinata key enzyme in flavonoid synthesis naringenin chalcone + 4 CoA + 3 CO2
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 ?

Organism

Organism UniProt Comment Textmining
Glycyrrhiza echinata
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
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 Glycyrrhiza echinata
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-coumaroyl-CoA + 3 malonyl-CoA key enzyme in flavonoid synthesis Glycyrrhiza echinata naringenin chalcone + 4 CoA + 3 CO2
-
 ?
malonyl CoA + 4-coumaroyl-CoA + NADH
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 Glycyrrhiza echinata 6'-deoxychalcone + CoA + CO2 + NAD+
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 ?
malonyl-CoA + 4-coumaroyl-CoA
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 Glycyrrhiza echinata naringenin chalcone + CoA + CO2 in the presence of NADH liquiritigenin i.e. 5-deoxyflavanone is formed as a byproduct ?
malonyl-CoA + 4-coumaroyl-CoA + NADPH
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 Glycyrrhiza echinata 5'-deoxyflavanone + CoA + CO2 + NADP+
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 ?