Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | Homo sapiens | - |
CoA + O-acylcarnitine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pulmonary artery endothelial cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + L-carnitine | - |
Homo sapiens | CoA + O-acylcarnitine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carnitine acetyl transferase | - |
Homo sapiens |
CRAT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | silencing the CrAT gene disrupts cellular carnitine homeostasis, reduces the expression of mitochondrial superoxide dismutase 2 and results in an increase in oxidative stress within the mitochondrion | Homo sapiens |