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Literature summary for 2.3.1.65 extracted from

  • Czuba, B.; Vessey, D.A.
    Structural characterization of cholylcoenzyme A: glycine-taurine N-acyltransferase and a covalent substrate intermediate (1986), J. Biol. Chem., 261, 6260-6263.
    View publication on PubMed
Search for more literature for 2.3.1.65

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
 amino acid composition Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
choloyl-CoA + glycine Bos taurus conjugation of bile acids in the liver with glycine or taurine prior to being secreted into the bile duct CoA + glycocholate
-
 ?
choloyl-CoA + taurine Bos taurus conjugation of bile acids in the liver with glycine or taurine prior to being secreted into the bile duct CoA + taurocholate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Reaction

Reaction Comment Organism Reaction ID
choloyl-CoA + glycine = CoA + glycocholate ping-pong mechanism Bos taurus
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
choloyl-CoA + glycine
-
 Bos taurus CoA + glycocholate
-
 ?
choloyl-CoA + glycine conjugation of bile acids in the liver with glycine or taurine prior to being secreted into the bile duct Bos taurus CoA + glycocholate
-
 ?
choloyl-CoA + taurine
-
 Bos taurus CoA + taurocholate
-
 ?
choloyl-CoA + taurine conjugation of bile acids in the liver with glycine or taurine prior to being secreted into the bile duct Bos taurus CoA + taurocholate
-
 ?
additional information in absence of amino acid substrate choloyl-CoA is cleaved with the release of CoA and formation of a covalent cholate-enzyme complex Bos taurus ?
-
 ?