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Literature summary for 2.3.1.6 extracted from

  • Loennerberg, P.; Lendahl, U.; Funakoshi, H.; Aerhlund-Richter, L.; Persson, H.; Ibanez, C.F.
    Regulatory region in choline acetyltransferase gene directs developmental and tissue-specific expression in transgenic mice (1995), Proc. Natl. Acad. Sci. USA, 92, 4046-4050.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in FR3T3 fibroblasts, SN6 cells and transgenic mice, a 3800-bp 5'flanking segment from the rat ChAT gene promotor directed cell type-specific expression of a reporter gene in cholinergic cells. A 2342-bp segment from the 5' flanking region of the ChAT gene behaves as an enhancer in cholinergic cells but as a repressor in noncholinergic cells in an orientation-independent manner Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + choline
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Rattus norvegicus acetylcholine + CoA
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