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Literature summary for 2.3.1.6 extracted from
- Choline acetyltransferase: purification and characterization (1980), J. Neurosci. Res., 5, 85-115.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3-Bromoacetonyltrimethylammonium bromide | - |
Homo sapiens |  |
| Acyloylcholine | - |
Bos taurus | |
| Acyloylcholine | - |
Drosophila melanogaster | |
| Acyloylcholine | - |
Homo sapiens | |
| Acyloylcholine | - |
Rattus norvegicus | |
| Acyloylcholine | - |
Tetronarce californica | |
| bromoacetyl-S-CoA | - |
Bos taurus | |
| Choline mustard aziridinium salt | - |
Bos taurus | |
| Choline mustard aziridinium salt | - |
Drosophila melanogaster | |
| Choline mustard aziridinium salt | - |
Homo sapiens | |
| Choline mustard aziridinium salt | - |
Rattus norvegicus | |
| Choline mustard aziridinium salt | - |
Tetronarce californica | |
| N-Methyl-4-(1-naphthylvinyl)pyridine | - |
Bos taurus | |
| N-Methyl-4-(1-naphthylvinyl)pyridine | - |
Drosophila melanogaster | |
| N-Methyl-4-(1-naphthylvinyl)pyridine | - |
Homo sapiens | |
| N-Methyl-4-(1-naphthylvinyl)pyridine | - |
Rattus norvegicus | |
| N-Methyl-4-(1-naphthylvinyl)pyridine | - |
Tetronarce californica | |
| Styrylpyridinium salts | - |
Bos taurus | |
| Styrylpyridinium salts | - |
Drosophila melanogaster | |
| Styrylpyridinium salts | - |
Homo sapiens | |
| Styrylpyridinium salts | - |
Rattus norvegicus | |
| Styrylpyridinium salts | - |
Tetronarce californica | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| additional information | - |
overview | Drosophila melanogaster |
| additional information | - |
overview | Homo sapiens |
| additional information | - |
overview | Rattus norvegicus |
| additional information | - |
overview | Bos taurus |
| additional information | - |
overview | Tetronarce californica |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Drosophila melanogaster | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Tetronarce californica | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
| overview procedures | Tetronarce californica |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Drosophila melanogaster | - |
| brain | - |
Homo sapiens | - |
| brain | - |
Rattus norvegicus | - |
| brain | - |
Bos taurus | - |
| brain | - |
Tetronarce californica | - |
| placenta | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
overview: assay methods | Drosophila melanogaster |
| additional information | - |
overview: assay methods | Homo sapiens |
| additional information | - |
overview: assay methods | Rattus norvegicus |
| additional information | - |
overview: assay methods | Bos taurus |
| additional information | - |
overview: assay methods | Tetronarce californica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + choline | - |
Drosophila melanogaster | acetylcholine + CoA | - |
? | |
| acetyl-CoA + choline | - |
Homo sapiens | acetylcholine + CoA | - |
? | |
| acetyl-CoA + choline | - |
Rattus norvegicus | acetylcholine + CoA | - |
? | |
| acetyl-CoA + choline | - |
Bos taurus | acetylcholine + CoA | - |
? | |
| acetyl-CoA + choline | - |
Tetronarce californica | acetylcholine + CoA | - |
? | |
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