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Literature summary for 2.3.1.59 extracted from

  • Payie, K.G.; Clarke, A.J.
    Characterization of gentamicin 2'-N-acetyltransferase from Providencia stuartii: its use of peptidoglycan metabolites for acetylation of both aminoglycosides and peptidoglycan (1997), J. Bacteriol., 179, 4106-4114.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Providencia stuartii enzyme may have a physiological role in secondary metabolism, its activity on aminoglycosides is simply fortouitous ?
-
 ?

Organism

Organism UniProt Comment Textmining
Providencia stuartii
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Providencia stuartii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + tobramycin
-
 Providencia stuartii CoA + N2'-acetyltobramycin
-
 ?
acetyl-CoA of soluble fragments of peptidoglycan + tobramycin
-
 Providencia stuartii ?
-
 ?
additional information enzyme may have a physiological role in secondary metabolism, its activity on aminoglycosides is simply fortouitous Providencia stuartii ?
-
 ?
N-acetyl-D-glucosamine + tobramycin
-
 Providencia stuartii D-glucosamine + N2'-acetyltobramycin
-
 ?