Literature summary for 2.3.1.57 extracted from

Liu, B.; Sun, H.; Wang, W.; Li, W.; Yan, Y.F.; Chen, S.M.; Yang, Y.P.; Xu, C.X.; Xin, J.X.; Liu, X.X.
Adenovirus vector-mediated upregulation of spermidine /spermine N1-acetyltransferase impairs human gastric cancer growth in vitro and in vivo (2009), Cancer Sci., 100, 2126-2132.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of SSAT in MGC803 and SGC7901 cells, two gastric cancer cell lines, using an adenoviral vector, recombinant enzyme expression inhibits cell growth in vitro and in vivo, Ad-SSAT arrests gastric cancer cells in S phase, mediated through downregulation of the cyclin A-E2F signaling pathway, polyamine contents in the cells, overview	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
spermidine /spermine N1-acetyltransferase	-	Homo sapiens
SSAT	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	antitumorigenicity of upregulated SSAT	up

General Information

General Information	Comment	Organism
metabolism	SSAT is the rate-limiting enzyme of polyamine catabolism	Homo sapiens

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Release 2023.1 (January 2023)