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Literature summary for 2.3.1.57 extracted from

  • Marverti, G.; Giuseppina Monti, M.; Pegg, A.E.; McCloskey, D.E.; Bettuzzi, S.; Ligabue, A.; Caporali, A.; DArca, D.; Moruzzi, M.S.
    Spermidine/spermine N1-acetyltransferase transient overexpression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin (2005), Carcinogenesis, 26, 1677-1686.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
transfection of the SSAT repressed C13 cells with two expression vectors driving human SSAT overexpression by diverse promoters. SSAT overexpression inhibits cell growth and enhances growth sensitivity to N1,N12-bis(ethyl)spermine in C13 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
ovary cancer cell C13 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + spermidine
-
Homo sapiens CoA + N1-acetylspermidine
-
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