Application | Comment | Organism |
---|---|---|
medicine | metabolic activation by isoforms 1 and 2 of 3-nitrobenzanthrone and N-acetyl-N-hydroxy-3-aminobenzantrone, 2 compounds with high mutagenic and genotoxic potential, formation of DNA adducts | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of isoforms 1 and 2 in chinese hamster lung fibroblast derived cell line V79MZ and in TA1538-derived Salmonella typhimurium strains | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | metabolic activation by isoforms 1 and 2 of 3-nitrobenzanthrone and N-acetyl-N-hydroxy-3-aminobenzantrone, 2 compounds with high mutagenic and genotoxic potential, formation of DNA adducts | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoforms NAT1 and NAT2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | metabolic activation by isoforms 1 and 2 of 3-nitrobenzanthrone and N-acetyl-N-hydroxy-3-aminobenzantrone, 2 compounds with high mutagenic and genotoxic potential, formation of DNA adducts | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NAT | - |
Homo sapiens |