Literature summary for 2.3.1.50 extracted from

Lowther, J.; Charmier, G.; Raman, M.C.; Ikushiro, H.; Hayashi, H.; Campopiano, D.J.
Role of a conserved arginine residue during catalysis in serine palmitoyltransferase (2011), FEBS Lett., 585, 1729-1734.

Search for more literature for 2.3.1.50

Cloned(Commentary)

Cloned (Comment)	Organism
-	Rhizorhabdus wittichii

Protein Variants

Protein Variants	Comment	Organism
R370A	strictly conserved in all prokaryotic enzymes and the Icb2 subunit of eukaryotic enzymes, no catalytic activity	Rhizorhabdus wittichii
R370K	strictly conserved in all prokaryotic enzymes and the Icb2 subunit of eukaryotic enzymes, 3% catalytic activity of wild type enzyme	Rhizorhabdus wittichii

Organism

Organism	UniProt	Comment	Textmining
Rhizorhabdus wittichii	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Rhizorhabdus wittichii

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
palmitoyl-CoA + L-serine	-	Rhizorhabdus wittichii	3-dehydrosphinganine + CoA + CO2	-	?

Synonyms

Synonyms	Comment	Organism
serine palmitoyltransferase	-	Rhizorhabdus wittichii

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Rhizorhabdus wittichii

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Release 2023.1 (January 2023)