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Literature summary for 2.3.1.50 extracted from

  • Hong, K.K.; Cho, H.R.; Ju, W.C.; Cho, Y.; Kim, N.I.
    A study on altered expression of serine palmitoyltransferase and ceramidase in psoriatic skin lesion (2007), J. Korean Med. Sci., 22, 862-867.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine decreased expression of SPT protein is one of the important causative factors for decreased ceramide levels in psoriasis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis protein expression of SPT in both psoriatic epidermis and non-lesional epidermis is investigated. Expression of SPT in psoriatic epidermis is significantly less than that of the non-lesional epidermis, which is inversely correlated with PASI score Homo sapiens
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Synonyms

Synonyms Comment Organism
serine palmitoyltransferase
-
Homo sapiens
SPT
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Homo sapiens