Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme activity and expression in the heart is not affected by high-fat feeding | Rattus norvegicus | |
pioglitazone | increases the enzyme activity in vitro and in vivo independent of standard or high-fat diet | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme activity and expression in the heart is not affected by high-fat feeding | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the enzyme activity and expression in the heart is not affected by high-fat feeding | ? | - |
? | |
palmitoyl-CoA + L-serine | Rattus norvegicus | the enzyme is involved in the ceramide metabolism, overview | CoA + 3-dehydro-D-sphinganine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
isozyme SPT2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | isozyme SPT2 | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme activity and expression in the heart is not affected by high-fat feeding | Rattus norvegicus | ? | - |
? | |
palmitoyl-CoA + L-serine | - |
Rattus norvegicus | CoA + 3-dehydro-D-sphinganine + CO2 | - |
? | |
palmitoyl-CoA + L-serine | the enzyme is involved in the ceramide metabolism, overview | Rattus norvegicus | CoA + 3-dehydro-D-sphinganine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
serine palmitoyltransferase | - |
Rattus norvegicus |
SPT | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.3 | - |
about, assay at | Rattus norvegicus |