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Literature summary for 2.3.1.5 extracted from

  • Uno, Y.; Murayama, N.; Yamazaki, H.
    Molecular and functional characterization of N-acetyltransferases NAT1 and NAT2 in cynomolgus macaque (2018), Chem. Res. Toxicol., 31, 1269-1276 .
    View publication on PubMed
Search for more literature for 2.3.1.5

Organism

Organism UniProt Comment Textmining
Macaca fascicularis A0A4Y1K7T4 isoform NAT2
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Macaca fascicularis A0A4Y1K7V2 isoform NAT1, a total of 9 transcript variants are found and contain 1-4 exons with the coding region largely conserved with human NAT1
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Source Tissue

Source Tissue Comment Organism Textmining
jejunum abundant expression Macaca fascicularis
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kidney abundant expression Macaca fascicularis
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liver abundant expression Macaca fascicularis
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liver most abundant expression Macaca fascicularis
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testis abundant expression Macaca fascicularis
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 2-aminofluorene
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 Macaca fascicularis CoA + N-acetyl-2-aminofluorene
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 ?
acetyl-CoA + 4-aminobenzoic acid
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 Macaca fascicularis CoA + N-acetyl-4-aminobenzoate
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 ?
acetyl-CoA + isoniazid
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 Macaca fascicularis CoA + N-acetyl-isoniazid
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 ?
acetyl-CoA + sulfamethazine
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 Macaca fascicularis CoA + N-acetylsulfamethazine
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 ?