Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P18440 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HT-29 cell | - |
Homo sapiens | - |
MDA-MB-231 cell | - |
Homo sapiens | - |
MDA-MB-436 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
NAT1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | following NAT1 knockdown with shRNA, acetylation of p-aminobenzoylglutamate is significantly decreased, while there are no changes in intracellular p-aminobenzoylglutamate or the components of the SAM cycle. The flux of homocysteine in the medium is different following NAT1 knockdown after the methionine content is exhausted. NAT1 knockdown inhibits the methionine salvage pathway in HT-29 cells but not in HeLa or MDA-MB-436 cells | Homo sapiens |