Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Benzyl isothiocyanate | - |
Homo sapiens | |
additional information | not inhibited by N-methylphenethylamine. GSH or dithiothreitol are unable to reactivate significantly inhibited isoform NAT1 | Homo sapiens | |
phenethyl isothiocyanate | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
His-select nickel resin column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl acetate + 4-aminobenzoic acid | - |
Homo sapiens | 4-nitrophenol + N-acetyl-4-aminobenzoate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NAT1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.007 | - |
at pH 7.5 and 37°C | Homo sapiens | Benzyl isothiocyanate | |
0.015 | - |
at pH 7.5 and 37°C | Homo sapiens | phenethyl isothiocyanate |