Literature summary for 2.3.1.5 extracted from

Tiang, J.M.; Butcher, N.J.; Minchin, R.F.
Small molecule inhibition of arylamine N-Acetyltransferase Type I inhibits proliferation and invasiveness of MDA-MB-231 breast cancer cells (2010), Biochem. Biophys. Res. Commun., 393, 95-100.

Search for more literature for 2.3.1.5

Application

Application	Comment	Organism
medicine	knock-down of enzymeby lentiviral shRNA reduces the invasion potential of MDA-MB-231 cells. Enzymic activity may be important in breast cancer growth and metastasis	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
(5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one	i.e. Rhod-o-hp. Significant reduction of cell growth by increasing the percent of MDA-MB-231 cells in G2/M phase of the cell cycle, and reduction of the ability of cells to grow in soft agar	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
MDA-MB-231 cell	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	knock-down of enzyme by lentiviral shRNA reduces the invasion potential of MDA-MB-231 cells. Enzymic activity may be important in breast cancer growth and metastasis	Homo sapiens

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Release 2023.1 (January 2023)