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Literature summary for 2.3.1.5 extracted from

  • Kawamura, A.; Graham, J.; Mushtaq, A.; Tsiftsoglou, S.A.; Vath, G.M.; Hanna, P.E.; Wagner, C.R.; Sim, E.
    Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening (2005), Biochem. Pharmacol., 69, 347-359.
    View publication on PubMed
Search for more literature for 2.3.1.5

General Stability

General Stability Organism
no refolding after thermal denaturation Mesocricetus auratus

Inhibitors

Inhibitors Comment Organism Structure
acetoacetyl-CoA 0.1 mM, 44% inhibition Mesocricetus auratus
butyryl-CoA 0.1 mM, 28% inhibition Mesocricetus auratus
glutaryl CoA 0.1 mM, 34% inhibition Mesocricetus auratus
hexanoyl-CoA 0.1 mM, 24% inhibition Mesocricetus auratus
malonyl-CoA 0.1 mM, 11 inhibition Mesocricetus auratus
octanoyl-CoA 0.1 mM, 74% inhibition Mesocricetus auratus
succinyl-CoA 0.1 mM, 96% inhibition Mesocricetus auratus

Organism

Organism UniProt Comment Textmining
Mesocricetus auratus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant shNAT2 Mesocricetus auratus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 2-aminofluorene
-
 Mesocricetus auratus CoA + 2-acetylaminofluorene
-
 ?
acetyl-CoA + 3,4-dichloroaniline
-
 Mesocricetus auratus ?
-
 ?
acetyl-CoA + 4-aminobenzoic acid
-
 Mesocricetus auratus CoA + 4-acetylaminobenzoic acid
-
 ?
acetyl-CoA + 4-aminosalicylic acid
-
 Mesocricetus auratus CoA + 4-acetylamino-2-hydroxybenzoate
-
 ?
acetyl-CoA + 4-anisidine
-
 Mesocricetus auratus CoA + 4-methoxyacetanilide
-
 ?
acetyl-CoA + 4-bromoaniline
-
 Mesocricetus auratus CoA + 4-bromoacetanilide
-
 ?
acetyl-CoA + 4-chloroaniline
-
 Mesocricetus auratus CoA + 4-chloroacetanilide
-
 ?
acetyl-CoA + 4-ethoxyaniline
-
 Mesocricetus auratus CoA + 4-ethoxyacetanilide
-
 ?
acetyl-CoA + 4-hexyloxyaniline
-
 Mesocricetus auratus CoA + 4-hexyloxyacetanilide
-
 ?
acetyl-CoA + 4-iodoaniline
-
 Mesocricetus auratus CoA + 4-iodoacetanilide
-
 ?
acetyl-CoA + 5-aminosalicylic acid
-
 Mesocricetus auratus CoA + 5-acetylamino-2-hydroxybenzoate
-
 ?
acetyl-CoA + butoxyaniline
-
 Mesocricetus auratus CoA + 4-butoxyacetanilide
-
 ?
additional information no acetylation of sulfamethazine and procainamide Mesocricetus auratus ?
-
 ?

Synonyms

Synonyms Comment Organism
NAT2
-
 Mesocricetus auratus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
additional information
-
 no refolding after thermal denaturation Mesocricetus auratus