Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + [protein]-L-lysine | Homo sapiens | - |
CoA + [protein]-N6-acetyl-L-lysine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O14929 | - |
- |
Homo sapiens | Q09472 | - |
- |
Homo sapiens | Q92793 | - |
- |
Homo sapiens | Q92830 | - |
- |
Homo sapiens | Q92831 | - |
- |
Homo sapiens | Q92993 | - |
- |
Homo sapiens | Q9H7Z6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + [protein]-L-lysine | - |
Homo sapiens | CoA + [protein]-N6-acetyl-L-lysine | - |
? | |
additional information | substrate site specificity, overview | Homo sapiens | ? | - |
- |
Synonyms | Comment | Organism |
---|---|---|
CREBBP | - |
Homo sapiens |
EP300 | - |
Homo sapiens |
HAT | - |
Homo sapiens |
histone acetyltransferases | - |
Homo sapiens |
KAT | - |
Homo sapiens |
Kat2A | - |
Homo sapiens |
Kat2b | - |
Homo sapiens |
KAT5 | - |
Homo sapiens |
KAT8 | - |
Homo sapiens |
lysine acetyltransferase | - |
Homo sapiens |
lysine acetyltransferase 2A | - |
Homo sapiens |
lysine acetyltransferase 2B | - |
Homo sapiens |
lysine acetyltransferase 5 | - |
Homo sapiens |
lysine acetyltransferase 8 | - |
Homo sapiens |
p300 HAT | UniProt | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | screening of 544 human HAT-specific sites for acetylation by different HATs. Development the GPS 2.2 algorithm for the prediction of APC/C recognition motifs such as D-boxes and KEN-boxes proteins. The algorithm comprises two major parts, including the scoring strategy and performance improvement, method, overview | Homo sapiens |
physiological function | protein acetylation catalyzed by specific histone acetyltransferases (HATs) is an essential posttranslational modification (PTM) and involved in the regulation a broad spectrum of biological processes in eukaryotes | Homo sapiens |